ISB (in silico breeding) Released as One General Computer Tool for the Prediction by Simulation in Plant Breeding

Computer simulation has been widely used in many scientific fields and disciplines. Simulation in plant breeding can help to investigate many what-if crossing and selection scenarios in plant breeding, allow many scenarios to be tested and compared in silico in a short period of time, and finally let the breeders make important decisions before conducting resource-demanding field experiments.

Cultivars in plant production can be classified into three major categories by the method of propagation and genetic constitution. Breeding techniques for the three categories of cultivars are quite different. However, they share many common attributes from the genetics point of view. Blib is a multi-module platform which can handle complex genetic effects and models, such as mutation, cytoplasm effect, cyto-nucleus interaction, and epistasis networks. ISB (abbreviated from i n silico breeding) is one major and unified application module of Blib that simulates the three categories of breeding programs for developing clonal, pure-line and hybrid cultivars in plants.

We spent a large amount of efforts and resources developing Blib together with ISB and other Blib application modules. For better service and further improvement, we wish each user could contribute a limited amount of fund to have the license to access and use ISB in one personal computer.

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